ВЗАИМНЫЕ ЭФФЕКТЫ САХАРНОГО ДИАБЕТА, ОЖИРЕНИЯ И SARS-COV-2
Аннотация
С момента первой вспышки SARS-Cov-2 в Китае большое внимание медицинского сообщества было уделено людям с сахарным диабетом, так как хорошо известно, что сахарный диабет повышает риск развития ряда инфекционных заболеваний. Причина этого многофакторная: возраст, пол, этническая принадлежность, сопутствующие заболевания, такие как гипертония, сердечно-сосудистые заболевания, ожирение, а также провоспалительное и прокоагулянтное состояние – все это способствует более тяжелому течению SARS-Cov-2 у пациентов с сахарным диабетом. Более того, тяжелая инфекция SARS-Cov-2 сама по себе может представлять собой ухудшающий фактор для людей с сахарным диабетом, поскольку она может вызвать острые метаболические осложнения через прямое негативное воздействие на функцию β-клеток.
Данный обзор призван обеспечить системную оценку потенциальных прогностических факторов и взаимных эффектов у пациентов с сахарным диабетом, ожирением и SARS-Cov-2.
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