СТАТИН-ИНДУЦИРОВАННЫЕ МЕХАНИЗМЫ НАРУШЕНИЙ УГЛЕВОДНОГО ОБМЕНА

  • Л. В. Никонова УО "Гродненский государственный медицинский университет", Гродно, Беларусь
  • С. В. Тишковский УО "Гродненский государственный медицинский университет", Гродно, Беларусь https://orcid.org/0000-0002-6970-276X
  • О. А. Шидловская Ошмянская центральная районная больница, Ошмяны, Беларусь
Ключевые слова: статины, сахарный диабет 2 типа, клиническое исследование, инсулинорезистентность, углеводный обмен

Аннотация

Статины – препараты первой линии, которые используются для профилактики сердечно-сосудистых заболеваний. Они снижают риск развития инфаркта миокарда, инсульта, а также сердечно-сосудистой смерти в среднем на 25-30%. Несмотря на безопасность и относительную переносимость статинов, обсервационные, клинические исследования и мета-анализы показали, что статины могут повышать риск развития сахарного диабета 2 типа. Доказано, что статины повышают инсулинорезистентность и снижают
секрецию инсулина β-клетками поджелудочной железы.

Литература

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2021-05-17
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Никонова ЛВ, Тишковский СВ, Шидловская ОА. СТАТИН-ИНДУЦИРОВАННЫЕ МЕХАНИЗМЫ НАРУШЕНИЙ УГЛЕВОДНОГО ОБМЕНА. Журнал ГрГМУ (Journal GrSMU) [Интернет]. 17 май 2021 г. [цитируется по 24 май 2024 г.];19(2):147-52. доступно на: http://journal-grsmu.by/index.php/ojs/article/view/2581

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