ФУНКЦИОНАЛЬНЫЕ ПРОБЫ В ПРАКТИКЕ ЭНДОКРИНОЛОГА
Аннотация
Доля пациентов с патологией эндокринной системы постоянно увеличивается во всех экономически развитых странах мира. Около 8% населения Республики Беларусь имеют эндокринную патологию, не считая избыточную массу тела и ожирение. Ежедневно врачи разных специальностей сталкиваются с пациентами с эндокринопатиями. Во многих случаях для определения дисфункции эндокринного органа и уровня нарушения его регуляции достаточно определение базального содержания гормона и его регуляторного фактора. При этом данных исследований не всегда является достаточно для точной оценки функционального состояния отдельных эндокринных органов, что требует проведения специальных функциональных проб. Данные пробы в эндокринологической практике являются обязательной частью лабораторной верификации болезней эндокринной системы. Функциональные пробы (стимуляционные и супрессивные) основаны на механизме обратной связи в системе гипоталамус-гипофиз-периферическая эндокринная железа. Также могут быть варианты проб при наличии внегипофизарного регуляторного фактора. Проведение функциональных проб позволяет предотвратить диагностическую ошибку, более точно установить диагноз при патологии эндокринной системы и назначить адекватное лечение согласно клиническим протоколам.
Литература
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