РОЛЬ АДЕНОЗИНА В РЕГУЛЯЦИИ ФУНКЦИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ
Аннотация
В настоящем обзоре рассмотрены основные сердечно-сосудистые эффекты аденозина. Аденозин играет особо важную роль в адаптации миокарда к ишемии и гипоксии. В частности, он является одним из важнейших медиаторов ишемического прекондиционирования миокарда. Аденозин участвует в регуляции сосудистого тонуса. Анализ литературных данных и результатов собственных исследований позволяет предположить, что сосудорасширяющий эффект аденозина частично опосредован эндотелиальным оксидом азота. Кроме того, аденозин обладает антиаритмическими свойствами и используется при суправентрикулярных тахиаритмиях.
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