РОЛЬ АДЕНОЗИНА В РЕГУЛЯЦИИ ФУНКЦИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ

  • В. И. Козловский УО "Гродненский государственный медицинский университет"
  • В. В. Зинчук УО "Гродненский государственный медицинский университет"
  • П. Б. Станкевич УО "Гродненский государственный медицинский университет"
  • С. Хлопицкий Ягеллонский университет, г. Краков
Ключевые слова: аденозин, ишемия миокарда, ишемическое прекондиционирование, сосудорасширяющий эффект, оксид азота, антиаритмические свойства

Аннотация

В настоящем обзоре рассмотрены основные сердечно-сосудистые эффекты аденозина. Аденозин играет осо­бо важную роль в адаптации миокарда к ишемии и гипоксии. В частности, он является одним из важнейших медиаторов ишемического прекондиционирования миокарда. Аденозин участвует в регуляции сосудистого то­нуса. Анализ литературных данных и результатов собственных исследований позволяет предположить, что сосудорасширяющий эффект аденозина частично опосредован эндотелиальным оксидом азота. Кроме того, аденозин обладает антиаритмическими свойствами и используется при суправентрикулярных тахиаритмиях.

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Козловский ВИ, Зинчук ВВ, Станкевич ПБ, Хлопицкий С. РОЛЬ АДЕНОЗИНА В РЕГУЛЯЦИИ ФУНКЦИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ. Журнал ГрГМУ (Journal GrSMU) [Интернет]. 4 ноябрь 2015 г. [цитируется по 29 март 2024 г.];(1(17):49-3. доступно на: http://journal-grsmu.by/index.php/ojs/article/view/1173

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