ГЕНЕТИЧЕСКИЕ ПРЕДПОСЫЛКИ К РАЗВИТИЮ СЕПСИСА



DOI: http://dx.doi.org/10.25298/2221-8785-2019-17-1-5-10


Р. Э. Якубцевич (R. E. Yakubtsevich)

Аннотация


Цель проведенного обзора литературы – обобщить результаты современных взглядов на генетические предпосылки к развитию сепсиса. Проанализировано 28 русскоязычных и англоязычных источников. Внимание уделено разным типам однонуклеотидных полиморфизмов, наличие которых способствует развитию сепсиса. Результаты приведенных исследований свидетельствуют о существовании взаимосвязи генетического полиморфизма каждого человека и риска развития септического процесса, его тяжести и исхода. На основании информации о генетических особенностях каждого человека станут возможны индивидуальные подходы к лечению и профилактике сепсиса.


Ключевые слова


сепсис, однонуклеотидный полиморфизм, толл-подобные рецепторы

Полный текст:

Литература


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