Р. Э. Якубцевич (Yakubtsevich R. E.)


Целью проведенного обзора литературы было обобщить результаты современных взглядов на вопросы диагностики сепсиса. Проанализированы   53 русскоязычных и англоязычных источника. Внимание уделено новым маркерам ранней диагностики сепсиса, а также тяжелого сепсиса и его осложнений. Указано на целесообразность клинического определения прокальцитонина и пресепсина  как наиболее изученных маркеров сепсиса.

Ключевые слова

сепсис; синдром полиорганной дисфункции; острый респираторный дистресс-синдром; прокальцитонин; пресепсин; индол; интерлейкин

Полный текст:


Методы экстракорпоральной гемокоррекции и их влияние на продукты микробного метаболизма у пациентов с сепсисом / Р. Э. Якубцевич [и др.] // Анестезиология и реаниматология, N 5.- 2015, C. 67-70.

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Neutrophil CD64 expression as a diagnostic marker for sepsis in adult patients: a meta-analysis / X. Wang [et al] // Crit. Care.- 2015.- Vol. 19, N 1.- P. 245.

Persistent inflammation and immunosuppression: A common syndrome and new horizon for surgical intensive care / L. F. Gentile [et al] // J. Trauma Acute Care Surg.- 2012.- Vol. 72, N 6.- P. 1491–1501.

Plasma neutrophil-gelatinase-associated lipocalin and cystatin C could early diagnosecontrast-induced acute kidney injury in patients with renal insufficiency undergoing an elective percutaneous coronary intervention / X. L. Liu [et al] // Chin. Med. J. Engl.– 2012.– Vol. 125, N 6.– P. 1051–1056.

Procalcitonin for the differential diagnosis of infectious and non-infectious systemic inflammatory response syndrome after cardiac operation / Z. Dong [et al] // Zhonghua Wei Zhong Bing Ji Jiu Yi Xue.- 2014.- Vol. 26, N 7.- P. 478-479.

Procalcitonin is a marker of gram-negative bacteremia in patients with sepsis / S.Y. Guo [et al] // Am. J. Med. Sci.- 2015.- Vol. 349, N 6.- P. 499-504.

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Serum Concentrations of Interleukin-6, Procalcitonin, and C-Reactive Protein: Discrimination of Septical Complications and Systemic Inflammatory Response Syndrome after Pediatric Surgery / F. Neunhoeffer [et al] // Eur J. Pediatr. Surg.- 2015.- Vol. 2, P.- 134-138.

Serum interleukin 17 as an early prognostic biomarker of severe acute pancreatitis receiving continuous blood purification / S.R. Dai [et al] // Int. J. Artif. Organs.- 2015.- Vol. 38, N 4.- P.192-198.

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The clinical significance of circulating soluble RAGE in patients with severe sepsis / H. Matsumoto [et al] // Trauma Acute Care Surg.- 2015.- Vol. 21.- P. 123-127.

The DISPARITY Study: do gender differences exist in Surviving Sepsis Campaign resuscitation bundle completion, completion of individual bundle elements, or sepsis mortality? / T. E. Madsen [et al] // J. Crit. Care- 2014.- Vol. 29, N 3.- P. 473.

The Limulus Amebocyte Lysate assay may be unsuitable for detecting endotoxin in blood of healthy female subjects / A. Gnauck [et al] // J. Immunol. Methods.- 2015.- Vol. 416.- P. 146-156.

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Usefulness of presepsin (sCD14-ST) measurements as a marker for the diagnosis and severity of sepsis that satisfied diagnostic criteria of systemic inflammatory response syndrome / T. Shozushima [et al] // J. Infect. Chemother.- 2011.- Vol. 17, N 6.- P. 764-769.

Value of interleukin-27 as a diagnostic biomarker of sepsis in critically ill adults / J. Fu [et al] // Zhonghua Wei Zhong Bing Ji Jiu Yi Xue.- 2015.- Vol. 27, N 6.- P. 460-464.

Variations in organism-specific severe sepsis mortality in the United States: 1999-2008 / C. Ani [et al] // Crit. Care Med.- 2015.- Vol. 43, N 1.- P. 65-77.


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