ПАТОМОРФОЛОГИЧЕСКИЕ АСПЕКТЫ ФОРМИРОВАНИЯ ФИБРОЗА ПЕЧЕНИ ПРИ HCV-ИНФЕКЦИИ И ДРУГИХ ПОРАЖЕНИЯХ ПЕЧЕНИ: СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ

  • С. П. Лукашик УО «Белорусский государственный медицинский университет»
  • В. М. Цыркунов УО «Гродненский государственный медицинский университет»
Ключевые слова: фиброгенез, внутри- и внеклеточные факторы, регрессия

Аннотация

В обзоре представлены внутри- и внеклеточные механизмы фиброгенеза и спонтанной регрессии фиброза при различных повреждениях печени.

Литература

Бабак О. Я. Проблемы фиброгенеза неалкогольной жировой болезни печени/О.Я. Бабак//Сучасна гастроентералогия. -2007. -№ 4 (36). -С. 4-10.

Возможность обратимости цирроза печени (клинические и патогенетические предпосылки)/Ч.С. Павлов [и др.]//РЖГК. -2006. -№1. -С. 20-29.

Ультраструктурные реакции клеточных популяций печени при действии РНК-и ДНК-геномных вирусов гепатата В+С/Г. И. Непомнящих [и др.]//Бюлл. эксперим. биологии и медицины. -1999. -Т. 128. -№7. -С.101-105.

Хронический вирусный гепатит/под. ред. В. В. Серова, З. Г. Апросиной. -М.: Медицина, 2002. -384 с.

Шерлок Ш. Заболевания печени и желчных путей/Ш. Шерлок, Дж. Дули -М.: ГЭОТАР МЕДИЦИНА, 1999. -859 с.

Akuta N. Risk factors of hepatitis C virus-related liver cirrhosis in young adults: positive family history of liver disease and transporter associated with antigen processing 2(TAP2)*0201 allele/N. Akuta, K. Chayama, F. Suzuki//J. Med. Virol. -2001. -64(2):109-116.

Agarwal D. P. Genetic polymorphisms of alcohol metabolizing enzymes/D. P. Agarwal//Pathol. Biol. -2001. -49(9):703-709.

Arthur M. J. Reversibility of liver fibrosis and cirrhosis following treatment for hepatitis C/M. J. Arthur//Gastroenterology. -2002. -122(5):1525-1528.

Bataller R. Liver fibrosis/R. Bataller, D. A. Brenner//Journal of Clinical Investigation Volume. -2005. -№2. -Р.209 -218.

Bataller R. Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal/R. Bataller, K. E. North, D. A. Brenner//Hepatology. -2003. -37(3):493-503.

Bataller R. Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells/R. Bataller, Y.H. Paik, J. N. Lindquist//Gastroenterology. -2004. -126(2):529-540.

Bataller R. Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II/R. Bataller, P. Sancho-Bru, P. Gin^//Gastroenterology. -2003. -125(1):117-125.

Berenguer M. Severe recurrent hepatitis C after liver retransplantation for hepatitis C virus-related graft cirrhosis/M. Berenguer, M.Prieto, A. Palau//Liver Transpl. -2003. -9(3):228-235.

Boya P. Nuclear factor-kappa B in the liver of patients with chronic hepatitis C: decreased RelA expression is associated with enhanced fibrosis progression/P. Boya, E. Larrea, I. Sola//Hepatology. -2001. -34(5):1041-1048.

Canbay A. Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis/A. Canbay, H. Higuchi, S. F. Bronk//Gastroenterology. -2002. -123(4):1323-1330.

Cho J. J. An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis/J. J. Cho, B. Hocher, H. Herbst//Gastroenterology. -2000. -118(6):1169-1178.

Corpechot C. Apolipoprotein E polymorphism, a marker of disease severity in primary biliary cirrhosis?/C. Corpechot, P. Benlian, V. Barbu//J. Hepatol. -2001. -35(3):324-328.

Degoul F. Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease/F. Degoul, A. Sutton, A. Mansouri//Gastroenterology. -2001. -120(6):1468-1474.

Dixon J. B. Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss/J. B.Dixon, P. S.Bhathal, N. R. Hughes//Hepatology. -2004. -39(6):1647-1654.

Donaldson P. HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility/P. Donaldson, K. Agarwal, A. Craggs//Gut. -2001. -48(3):397-402.

Jдrvelдinen H. A. Promoter polymorphism of the CD 14 endotoxin receptor gene as a risk factor for alcoholic liver disease/H. A. Jдrvelдinen, A. Orpana, M. Perola//Hepatology. -2001. -33(5):1148-1153.

Hammel P. Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct/P. Hammel, A. Couvelard, D. O'Toole//N. Engl. J. Med. -2001. -344(6):418-423.

Ikejima K. Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat/K. Ikejima, Y. Takei, H. Honda//Gastroenterology. -2002. -122(5): 1399-1410.

Issa R. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking/R. Issa, X. Zhou, C. M.

Constandinou//Gastroenterology. -2004. -126(7):1795-1808.

Galli A. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro/A. Galli, D. W. Crabb, E. Ceni//Gastroenterology. -2002. -122(7):1924-1940.

Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells/A. Geerts//Semin. Liver Dis. -2001. -21(3). -Р. 311-335.

Gressner A.M. Roles of TGF-beta in hepatic fibrosis/A. M. Gressner, R. Weiskirchen, K. Breitkopf//Front Biosci. -2002. -1(7): d793-807.

Kamada Y. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin/Y. Kamada, S. Tamura, S. Kiso//Gastroenterology. -2003. -125(6):1796-1807.

Kinnman N. Peribiliary myofibroblasts in biliary type liver fibrosis/N. Kinnman, C. Housset//Front. Biosci. -2002. -7:496-503.

Lindquist J. N. Fibrogenesis. III. Posttranscriptional regulation of type I collagen/J. N. Lindquist, W. F. Marzluff, C. J. Parsons//Am. J. Physiol. Gastrointest. Liver Physiol. -2000. -279(3): 471-476.

Magness S. T. A dual reporter gene transgenic mouse demonstrates heterognity in hepatic fibrogenic cell populations/S. T. Magness, R. Bataller, L. Yang//Hepatology. -2004. -40:1151-1159.

Maher J. J. Acetaldehyde-induced stimulation of collagen synthesis and gene expression is dependent on conditions of cell culture: studies with rat lipocytes and fibroblasts/J. J. Maher, S. Zia, C. Tzagarakis//Alcohol Clin. Exp. Res. -1994. -18(2):403-409

Mann D.A. Transcriptional regulation of hepatic stellate cell activation/D. A. Mann, D. E. Smart//Gut. -2002. -50(6):891-6.

Marra F. Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat/F. Marra, M. C., Arrighi, M. Fazi//Hepatology. -1999. -30(4):951-958.

Marra F. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells/F. Marra, E. Efsen, R. G. Romanelli//Gastroenterology. -2000. -119(2):466-78.

Naito M. Differentiation and function of Kupffer cells/M. Naito, G. Hasegawa, Y. Ebe//Med. Electron Microsc. -2004. -37(1):16-28.

Oben J. A. Norepinephrine and neuropeptide Y promote proliferation and collagen gene expression of hepatic myofibroblastic stellate cells/J. A. Oben, S. Yang, H. Lin//Biochem. Biophys. Res. Commun. -2003. -302:685-690.

Oben J. A. Hepatic fibrogenesis requires sympathetic neurotransmitters/J. A. Oben, T. Roskams, S. Yang//Gut. -2004. -53(3):438-45.

Olaso E. DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells/E. Olaso, K. Ikeda, F. J. Eng//J. Clin. Invest. -2001. -108(9):1369-1378.

Ortiz V. Contribution of obesity to hepatitis C-related fibrosis progression/V. Ortiz, M. Berenguer, J. M. Rayon//Am. J. Gastroenterol. -2002. -97(9):2408-2414.

Pares A. Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage/A. Pares, J. Caballeria, M. Bruguera//J. Hepatol. 1986. -2(1). -Р. 33-42.

Powell E. E. Host genetic factors influence disease progression in chronic hepatitis C/E. E. Powell, C. J. Edwards-Smith, J. L. Hay//Hepatology. -2000. -31(4):828-833.

Ramadori G. Portal tract fibrogenesis in the liver/G. Ramadori, B. Saile//Lab. Invest. -2004. -84(2):153-159.

Safadi R. Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes. Gastroenterology/R. Safadi, M. Ohta, C. E. Alvarez//2004. -127(3):870-882.

Sahai A. Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model. Am. J. Physiol. Gastrointest. Liver Physio/A. Sahai, P. Malladi, H. Melin-Aldana//2004. -287(1):G264-G273.

Sasaki K. Mannose-binding lectin polymorphisms in patients with hepatitis C virus infection/K. Sasaki, A. Tsutsumi, N. Wakamiya//Scand. J. Gastroenterol. -2000. -35(9):960-965.

Schuppan D. Hepatitis C and liver fibrosis/D. Schuppan, A. Krebs, M. Bauer//Cell Death Differ. -2003. -10(1):S59-S67.

Schwabe R. F. Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration/R. F. Schwabe, R. Bataller, D. A. Brenner//Am. J. Physiol. Gastrointest. Liver Physiol. -2003. -285(5): G949-58.

Shek F. W. How can transforming growth factor beta be targeted usefully to combat liver fibrosis?/F. W. Shek, R. C. Benyon//Eur. J. Gastroenterol. Hepatol. -2004. -16(2):127-33.

Streetz K. L. Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases/K. L. Streetz, F. Tacke, L. Leifeld//Hepatology. -2003. -38(1):218-229.

Takehara T. Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses/T. Takehara//Gastroenterology. -2004. -127:1189-1197.

Ueberham E. Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis/E. Ueberham, R. L^, U. Ueberham//Hepatology. -2003. -37(5):1067-1078.

Wanless I. R. The pathogenesis of nonalcoholic steatohepatitis and other fatty liver diseases: a four-step model including the role of lipid release and hepatic venular obstruction in the progression to cirrhosis/I. R. Wanless, K. Shiota//Semin. Liver Dis. -2004. -24(1):99-106.

Wheeler M. D. The role of Kupffer cell oxidant production in early ethanol-induced liver disease/M. D. Wheeler, H. Kono, M. Yin//Free Radic. Biol. Med. -2001. -31(12):1544-1549.

Williams E. J. Relaxin inhibits effective collagen deposition by cultured hepatic stellate cells and decreases rat liver fibrosis in vivo/E. J. Williams, R. C. Benyon, N. Trim//Gut. -2001. -49(4):577-83.

Yu C. Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis/C. Yu, F. Wang, C. Jin//Am. J. Pathol.-2003. -163(4):1653-1662.

Yoshida T. SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis/T. Yoshida, H. Ogata, M. Kamio//J. Exp. Med. -2004. -199(12):1701-1707.




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2015-10-07
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Лукашик СП, Цыркунов ВМ. ПАТОМОРФОЛОГИЧЕСКИЕ АСПЕКТЫ ФОРМИРОВАНИЯ ФИБРОЗА ПЕЧЕНИ ПРИ HCV-ИНФЕКЦИИ И ДРУГИХ ПОРАЖЕНИЯХ ПЕЧЕНИ: СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ. Журнал ГрГМУ (Journal GrSMU) [Интернет]. 7 октябрь 2015 г. [цитируется по 25 декабрь 2024 г.];(1(25):8-13. доступно на: http://journal-grsmu.by/index.php/ojs/article/view/810

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