ИММУНОРЕАКТИВНОСТЬ NEUN, НЕЙРОГЛОБИНА И АТФСИНТАЗЫ В РАЗВИВАЮЩИХСЯ ГИСТАМИНЕРГИЧЕСКИХ НЕЙРОНАХ ГИПОТАЛАМУСА КРЫСЫ
Аннотация
Введение. Изучение иммунореактивности NeuN, Ngb и АТФ-синтазы в развивающихся гистаминергических нейронах представляет значительный интерес, учитывая важность и недостаточную изученность этих нейронов. Цель исследования. Оценка содержания NeuN, Ngb и АТФ-синтазы в гистаминергических нейронах ядра Е2 мозга крыс в динамике постнатального онтогенеза. Материал и методы. Исследование выполнено на 5, 10, 20, 45 и 90-суточных беспородных белых крысах с применением иммуногистохимических, цитофотометрических и статистических методов исследования. Результаты. В развивающихся гистаминергических нейронах мозга крыс с 5 по 90 сутки после рождения параллельно нарастает иммунореактивность МАО Б, NeuN, Ngb и АТФ-синтазы. Выводы. В ходе постнатального развития гистаминергических нейронов параллельно их структурно метаболическому становлению происходит синхронное возрастание иммунореактивности МАО Б, NeuN, Ngb и АТФ-синтазы.
Литература
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