УНИВЕРСАЛЬНЫЕ ПРИНЦИПЫ БАКТЕРИАЛЬНОЙ КОММУНИКАЦИИ
Аннотация
В статье представлена актуальная информация о феномене межклеточной коммуникации бактерий, ее роли в экспрессии генов вирулентности, в частности, распространении устойчивости к антибиотикам. Выделены базовые принципы функционирования кворума, присущие всем известным на сегодняшний день системам бактериальной коммуникации. Проанализированы основные сигнальные молекулы (аутоиндукторы) внутривидовой, межвидовой, эпинефриновой и пептидной связи. Оценена роль блокирования информационной связи (сигнальных молекул) между бактериями в качестве дополнительной стратегии против бактерий с экстремальной и полной антибиотикорезистентностью.
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