ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ДЛЯ ИЗУЧЕНИЯ САХАРНОГО ДИАБЕТА ЧАСТЬ I. АЛЛОКСАНОВЫЙ ДИАБЕТ
Аннотация
В обзоре обобщены данные литературы о модели аллоксан-индуцированного диабета у экспериментальных животных. Также проанализированы и обсуждены механизмы избирательного воздействия аллоксана на b-клетки поджелудочной железы. Сделано заключение, что основой патогенеза экспериментального диабета является взаимодействие различных биологических эффектов, вызываемых аллоксаном.
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