ПОЛУЧЕНИЕ ИНСУЛИН-ПРОДУЦИРУЮЩИХ КЛЕТОК ИЗ ЭМБРИОНАЛЬНЫХ И ИНДУЦИРОВАННЫХ ПЛЮРИПОТЕНТНЫХ СТВОЛОВЫХ КЛЕТОК
Аннотация
В обзоре обсуждается проблема получения инсулин-продуцирующих клеток из эмбриональных и индуцированных плюрипотентных стволовых клеток. Проанализированы результаты исследований крупных научных центров и лабораторий, работающих в этом направлении. Подробно рассмотрены сложные аспекты дифференцировки стволовых клеток в функционально зрелые инсулин-продуцирующие клетки. Показана необходимость дальнейшей оптимизации технологий их получения с целью использования генерированных клеток в клинической практике.
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