СОСТАВ ДУКТАЛЬНОГО СЕКРЕТА ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ ПРИ ХРОНИЧЕСКИХ ПАНКРЕАТИТАХ АЛКОГОЛЬНОЙ ЭТИОЛОГИИ

  • Л. А. Можейко УО "Гродненский государственный медицинский университет", Гродно, Беларусь
Ключевые слова: поджелудочная железа, дуктальная секреция, хронический алкогольный панкреатит

Аннотация

Цель обзора – представить анализ современных научных сведений об изменении состава дуктального секрета поджелудочной железы при хроническом алкогольном панкреатите. Показано, что токсическое воздействие алкоголя на клеточном уровне проявляется прежде всего недостаточной секрецией воды и карбонатов дуктулоцитами мелких протоков. Рассмотрена решающая роль дисфункции CFTR каналов в этих нарушениях. Обсуждены возможные механизмы участия трипсина, лактоферрина, литостатина и кальция в процессах преципитации и камнеобразования.

Литература

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2021-06-01
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Можейко ЛА. СОСТАВ ДУКТАЛЬНОГО СЕКРЕТА ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ ПРИ ХРОНИЧЕСКИХ ПАНКРЕАТИТАХ АЛКОГОЛЬНОЙ ЭТИОЛОГИИ. Журнал ГрГМУ (Journal GrSMU) [Интернет]. 1 июнь 2021 г. [цитируется по 27 май 2024 г.];17(5):495-9. доступно на: http://journal-grsmu.by/index.php/ojs/article/view/2608