СИНТЕЗ И СЕКРЕЦИЯ ИНСУЛИНА: РОЛЬ КАТИОНОВ ЦИНКА
Аннотация
Представлены литературные данные о роли цинка в процессинге инсулина в панкреатических β-клетках островков Лангерганса. Показано, что в качестве кофактора Zn2+ не только принимает участие в синтезе и депонировании гранул инсулина в везикулах, но и, высвобождаясь во внеклеточное пространство, является сигнальной молекулой для α-клеток.
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