АЛГОРИТМЫ НАЗНАЧЕНИЯ ХОЛЕКАЛЬЦИФЕРОЛА ДЛЯ ТЕРАПИИ И ПРОФИЛАКТИКИ D-ГИПОВИТАМИНОЗА ПРИ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИИ



DOI: http://dx.doi.org/10.25298/2221-8785-2019-17-4-436-444


Л. В. Якубова (L. V. Yakubova), В. А. Снежицкий (V. A. Snezhitskiy)

Аннотация


Цель работы – проанализировать литературные и собственные данные по назначению холекальциферола для терапии и профилактики D-гиповитаминоза при артериальной гипертензии (АГ) с учетом факторов риска и комбинированной антигипертензивной терапии. Результаты анализа литературных данных и выполненного нами проспективного, контролируемого, рандомизированного, сравнительного, одноцентрового клинического исследования 173 пациентов с АГ II степени с приемом холекальциферола в дозе 2000 МЕ/сутки на протяжении 3, 6 и более месяцев позволили предложить алгоритмы назначения холекальциферола для терапии и профилактики D-гиповитаминоза при АГ.

Ключевые слова


витамин D, артериальная гипертензия, дисфункция эндотелия, тиазидные диуретики, кальций, фосфор, дислипидемия

Полный текст:

Литература


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